1659-1734 Doctor Michel Sarrazin “The First Canadian Physiologist”

The Sarrazin lectureship was initiated in 1976, by the Society for a “Distinguished Speaker” to give a 1 hour lecture to the Society at its meeting and that the Lectureship would be called the “Sarrazin Lecture” in recognition of “the First Canadian Physiologist”.
 
Although nominations were initially solicited from the membership and the Lecturer selected by the Executive, it was subsequently felt appropriate for the outgoing President of the Society to be charged with making the selection of the speaker for the subsequent Annual Meeting.
 
The first Sarrazin Lecturer was Dr. Harold Copp, who presented his lecture at the Winter Meeting of the Society in 1977.
 

2018 Sarrazin Lecturer

Patricia Brubaker, PhD

 

 

Dr. Patricia Brubaker obtained her PhD at McGill University followed by post-doctoral studies at the University of Toronto, where she is currently Professor in the Departments of Physiology and Medicine. Since 1985, she has been actively involved in studies on the intestinal glucagon-like peptides, GLP-1 and GLP-2. Although GLP-1 mimetics are already used clinically to lower glycemia in patients with type 2 diabetes, Dr. Brubaker’s studies focus on the regulation of GLP-1 secretion as a possible new therapeutic approach for these patients, with recent discoveries demonstrating roles for SNARE proteins, circadian clock genes and the intestinal microbiome in regulating this intestinal hormone. Dr. Brubaker was also one of the original discovers of the intestinotrophic actions of GLP-2, an analogue of which has recently been approved as a first-in-class treatment for patients with short bowel syndrome. Her current studies on GLP-2 interrogate the mechanism of action of this novel intestinal growth hormone including, most notably, indirect pathways mediated through the stimulation of other growth factors. Dr. Brubaker has received several awards for her research, including the Canadian Diabetes Association Young Scientist Award (1998) and a Tier 1 Canada Research Chair in Vascular and Metabolic Biology (2000; renewed 2007; renewed 2015). She has published 190 papers in high-quality peer-reviewed journals and books, and has lectured both nationally and internationally on the topic of the glucagon-like peptides. Over the course of her career, she has trained 13 post-doctoral fellows, 43 graduate students and 141 undergraduate research project students, and she has won multiple awards from the University of Toronto for her teaching and trainee mentorship.

 

Sarrazin Lecturers

 

  1. 1977. Harold A. Copp (University of British Columbia) “Calcitonin and the regulation of internal calcium levels” Banff, Alberta.
  2. 1978. L.B. Jacques (University of Saskatchewan) “Heparin: its medical and physiological significance” Mont Ste. Marie, Québec.<
  3. 1979. F.C. (Hank) MacIntosh (McGill University) “The age of bioassay” or “My early stumbles on the trail of histamine and acetylcholine” Mount Orford, Québec.
  4. 1980. Herbert H. Jasper (McGill University, Université de Montréal) “Adventures of a neuroscientist” Banff, Alberta.
  5. 1981. Hans Selye (Université de Montréal) Award made (address to the Society not made due to illness). Ste. Adèle, Québec.
  6. 1982. A.M. Rappaport (University of Toronto) “The idea behind it all” Beaupré (Mont Sainte-Anne), Québec.
  7. 1983. Jack Kraicer (Queen’s University) “Mechanisms governing the release of growth hormone: Role of cyclic nucleotides and Ca2+” Vernon, British Columbia.
  8. 1984. Kresimir Krnjevic (McGill University) “Travels in physiology” Ste. Adèle, Québec.
  9. 1985. Hugh McLennan (University of British Columbia) “Michel Sarrazin, 1659-1734” Mont Rolland, Québec.
  10. 1986. Keith E. Cooper (University of Calgary) “Adventures in thermoregulation” Lake Louise, Alberta.
  11. 1987. Henry Friesen (University of Manitoba) ” Reflections on a snowy evening” Ste. Adèle, Québec.
  12. 1988. Vivian C. Abrahams (Queen’s University) “Early days in the making of one physiologist”. Ste. Jovite (Mt. Tremblant), Québec.
  13. 1989. John C. Brown (University of British Columbia) “The gastrointestinal hormones motilin and GIP” Whistler, British Columbia.
  14. 1990. Fernand Labrie (Université Laval) “Peripheral tissues are important sites of sex steroid formation in the human: A new field of endocrinology which extends from gene structure to therapy that prolongs life in prostate cancer” Beaupré (Mont Sainte-Anne),.Québec.
  15. 1991. Gordon J. Mogenson (University of Western Ontario) “Some aspects of limbic-motor integration: dopamine modulation of limbic inputs to ventral striatal neurons” Beaupré (Mont Sainte-Anne), Québec.
  16. 1992. Yves Lamarre (Université de Montréal) “Central mechanisms of tremor” Kimberley, British Columbia.
  17. 1993. Andrew S. French (University of Alberta) “The cockroach tactile spine” Ste. Jovite (Mt. Tremblant), Québec.
  18. 1994. John Ledsome (University of British Columbia) “The cardiac atria and the homeostasis of extracellular fluid volume” Lake Louise, Alberta.
  19. 1995. Jack Diamond (MacMaster University) Ste. Jovite (Mt. Tremblant), Québec.
  20. 1996. Geza T. Hetenyi (University of Ottawa) “The sweetness of life: glucose homeostasis” Lake Louise, Alberta.
  21. 1997. John C. Szerb (Dalhousie University) “When the going was good” Mont Gabriel, Québec.
  22. 1998. Leo P. Renaud (University of Ottawa) “The “NEURO” in neuroendocrine: what’s it got for physiologists?” Kimberley, BC.
  23. 1999. Michel Bergeron (Université de Montréal) “Cellular organization, organelle interrelationship: Terra nova.” Marble Mountain, Newfoundland.
  24. 2000. James P. Lund (McGill University, Université de Montréal) “Revelling in the joys of mastication”, Lake Louise, Alberta.
  25. 2001. Richard B. Stein (University of Alberta) “A personal odyssey from physics to physiology and prosthetics”, Mont Tremblant, Québec.
  26. 2002. Geoffry Melvill Jones (University of Calgary, McGill University) “Thrills and spills in a parapetitic life of messing about in labs”, Silver Star, BC.
  27. 2003. Harold L. Atwood (University of Toronto) “Insight by accident or insight by design?” Beaupré (Mont Sainte-Anne), Québec.
  28. 2004. John R. Challis (University of Toronto) “Preterm birth, fetal glucocorticoids, and the developmental programming of health and disease (DOHAD)”, Silver Star, BC.
  29. 2005. Alison M. Buchan (University of British Columbia) “A physiologist’s journey from neuroendocrinology to infectious diseases.” Beaupré (Mont Sainte-Anne), Québec.
  30. 2006. Alvin Shrier (McGill University) “The beat goes on”. Lake Louise, Alberta.
  31. 2007. Keir Pearson (University of Alberta) “Neurobiology of locomotion.” Beaupré (Mont Sainte-Anne), Québec.
  32. 2008. Quentin Pittman (University of Calgary) “Some like it hot: an inflammatory view of physiology”. Lake Louise, Alberta.
  33. 2009. John MacDonald (University of Western Ontario) “Adventures in NMDA receptors, phosphorylation and hippocampal synaptic plasticity”. Beaupré (Mont Sainte-Anne), Québec.
  34. 2010. Terrance P Snutch (University of British Columbia).  Halifax, N.S.
  35. 2011. Bruce McManus (University of British Columbia).  Ste. Adele, Quebec.
  36. 2012. Duncan Stewart (University of Ottawa).  Toronto, Ontario.
  37. 2013.  No Award
  38. 2014.  No Award
  39. 2015.  Kathleen Cullen (McGill University).  “”Where are we going? Sensing self-motion for perception and action.”  Vancouver, B.C.
  40. 2016. Douglas Crawford (York University). Toronto, Ontario.
  41. 2017. Serge Rossignol (Universite de Montreal). “The spinal brain.”  Montreal, Quebec.
  42. 2018. Sandra Davidge (University of Alberta). “Impact of pregnancy complications on maternal and offspring cardiovascular health”. Halifax, N.S.
  43. 2019. Patricia Brubaker (University of Toronto). Toronto, Ontario.